Abstract: The contents of 5 heavy metals (Cu, Zn, Pb, Cd and As) and their characteristics of metal enrichement in 12 marine organism species from Changhua river estuary in Hainan Island were analyzed, and their edible health risks were evaluated. The results showed that, except for As, the average contents of heavy metals in organisms were sequenced by crustaceans (shrimp and crabs) > bivalves > fish; the content of Zn was the highest, while that of Cd was the lowest, all the heavy metals contents did not exceed the standard of the Maximum Levels of Contaminations in Foods (GB 2762-2017). Bioconcentration factors (BCF) and Nonmetric Multidimensional Scaling (NMDS) analysis showed that organisms enriched metals from seawater easily, Cu and Zn were the common enriched metals by organisms. For different organism species, As was enriched obviously in the fishes, Pb was enriched in bivalves and shrimps stronger, while Cd was enriched in Portunus pelagicus significantly. The edible health risk assessment results showed that non-carcinogenic health risks were negligible, but long-term consumption of seafood may cause a potential carcinogenic risk. Monte Carlo simulation results showed that As was the main edible risk element, accounting for 56.44% and 89.63% of the total variance of non-carcinogenic and carcinogenic risk contributions, respectively, and oral ingestion rate (IR) contributed to health risk with low variance.