Abstract: Research on remote sensing retrieval of suspended sediment concentration in Hangzhou Bay by GF-1 satellites is an important task,because suspended sediment concentration is one of the important parameters of remote sensing inversion.The simulation of the GF-1 satellite data band settings were performed by using the observed data of the hyperspectrum in the Hangzhou bay,and the relationship between different band combination of remote sensing reflectance and suspended sediment concentration were analyzed.The suspended sediment concentration of satellite remote sensing inversion model was constructed and verified by the GF-1 satellites simulation data.The suspended sediment concentration in cross-sea bridge of Hangzhou bay estuary waters was inversed by using the GF-1 satellites,and the finding is that the cross sea bridge has certain influence on the distribution of suspended sediment,and suspended sediment has obvious difference on both sides cross sea bridge.