Abstract: The paper used suspended sediment concentration (SSC) data of the Pearl River on each season of 2014 and Landsat 8 multispectral data to do inversion and analysis. It is fond that SSC is lowest in winter but highest in summer, the intermediate valueinfluenced by runoff, moonsoon, seasonal upwelling is in spring and autumn. The value is higher along nearshore than offshore in winter. SSC is more higher in spring than in winter. The distribution of SSC is northeast-southwest trending and gradually decreasing. It is a wet period in summer that SSC is the highest. Higher value is concentrated on entrance, offshore value is lower. The distribution of SSC in autumn is higher value concentrationed on the top of the Pearl River and entrance.