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Volume 34 Issue 4
Jul.  2015
Article Contents

Citation:

Effects of benzo[a]pyrene exposure on biomarkers in Exopalaemon carinicauda liver

  • Received Date: 2014-03-20
    Accepted Date: 2014-05-29
  • Benzo[a]pyrene (BaP) is one of the most important pollutants in the marine environment.Effects of biomarkers which including EROD,GST,SOD,CAT,GPx,MDA in the liver of Exopalaemon carinicauda with BaP exposure and elimination were detected in the exposure period (fifteen days) and elimination period (fifteen days).The outcomes indicated that the activities of six biomarkers were significantly induced by BaP in the first day (P0.05) and exhibited a direct correlation with the concentration of BaP,then indicated a different change trend between six biomarkers.The activities of EROD continued to grow until it hit a steady state in ten days,the activities of GST continued to grow and then went down slightly in ten days,the activities of three antioxidant enzymes (SOD,CAT,GPx) gradually declined and lower than in the control group in fifteen days,the concentration of MDA continued to grow during the exposure period,established as a direct biomarker reflecting the oxidant stress.In the evacuation period,the lower concentration groups resumed quickly than the higher concentration groups,all biomarkers could resumed to the command level (P0.05),while the high concentration,in contrast,could not resumed to the command level (P0.05).The results of this experiment indicated that the E.Carinicauda possessed resume capacity,there were a certain degree difference between sensitivity of all bookmakers,factors including BaP concentration and exposure time had an important impression on six biomarkers activities.
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  • [1] 冯 涛,郑微云,洪万树,等.苯并(a)芘对大弹涂鱼肝脏芳烃羟化酶活性的影响[J].水产学报,2001,25(2):156-160.[9]任加云,潘鲁青,苗晶晶,等.苯并(a)芘和苯并(k)荧蒽混合物对栉孔扇贝毒理学指标的影响[J].环境科学学报,2006,26(7):1180-1186.[17]李 康,周忠良,陈立侨,等.苯并[a]芘对鲫鱼生物标志物的影响研究[J].环境科学研究,2006,19(1):91-95.[20]杨慧赞.苯并[a]芘在栉孔扇贝(Chlamys farreri)体内的毒代与毒效动力学研究[D].青岛:中国海洋大学,2008.
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Effects of benzo[a]pyrene exposure on biomarkers in Exopalaemon carinicauda liver

  • 1. East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China;
  • 2. College of Marine Sciences, Shanghai Ocean University, Shanghai 201306, China

Abstract: Benzo[a]pyrene (BaP) is one of the most important pollutants in the marine environment.Effects of biomarkers which including EROD,GST,SOD,CAT,GPx,MDA in the liver of Exopalaemon carinicauda with BaP exposure and elimination were detected in the exposure period (fifteen days) and elimination period (fifteen days).The outcomes indicated that the activities of six biomarkers were significantly induced by BaP in the first day (P0.05) and exhibited a direct correlation with the concentration of BaP,then indicated a different change trend between six biomarkers.The activities of EROD continued to grow until it hit a steady state in ten days,the activities of GST continued to grow and then went down slightly in ten days,the activities of three antioxidant enzymes (SOD,CAT,GPx) gradually declined and lower than in the control group in fifteen days,the concentration of MDA continued to grow during the exposure period,established as a direct biomarker reflecting the oxidant stress.In the evacuation period,the lower concentration groups resumed quickly than the higher concentration groups,all biomarkers could resumed to the command level (P0.05),while the high concentration,in contrast,could not resumed to the command level (P0.05).The results of this experiment indicated that the E.Carinicauda possessed resume capacity,there were a certain degree difference between sensitivity of all bookmakers,factors including BaP concentration and exposure time had an important impression on six biomarkers activities.

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